Vital Transformation understands the implications of new medical procedures, technologies and policies. We measure their impact on current clinical practices in close collaboration with health care professionals, researchers, and regulators. Through our web platform and client network, we are able to communicate our findings with international decision makers and stakeholders.
OUR RESEARCH
PREPRINT NEW RESEARCH: The Inflation Reduction Act’s Impact Upon Late-Stage R&D
Vital Transformation is preparing a new analysis with a total of 1148 secondary trials from 364 FDA-approved medicines, published from 2018 to 2025, obtained from Biomedtracker and clinicaltrials.gov. Using fractional multinomial logit, we model the share distribution of secondary indication studies across 19 disease groups and assess the change in this distribution post-IRA. We also assessed the number of secondary treatment studies pre- vs. post-IRA using multiple linear regression.
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Our clients include many of the world’s leading health care organisations.



























