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Join host Duane Schulthess on the Vital Health Podcast as he explores the groundbreaking Prime Rose Project, an initiative redefining the use of off-label drugs in oncology. Featuring insights from Dr. Hans Gelderblom, Chair of Medical Oncology at Leiden University Medical Center, and Sahar Barjesteh van Waalwijk van Doorn-Khosrovani, a member of the Dutch National Payers Evaluation Committee, this episode delves into the challenges and opportunities of drug rediscovery protocols. Learn how this innovative approach balances accessibility, affordability, and evidence-based treatments, transforming the landscape of personalized medicine across Europe.
Find all our communication projects on Better Science, Better Health
MORE RESEARCH
Innovation Requires a New Regulatory Framework to Improve Research and Development of New Medical Therapies
20th June, 2013
By Duane Schulthess
For targeted medicines, the current processes of regulatory evaluation, decision frameworks and delivery systems are limiting the implementation of new, better therapies. A healthcare ecosystem designed to enable innovation must also support R&D that is cost effective for all stakeholders and make-good on the promise that innovative medicines can effectively deliver the right prevention and treatment to the right patient at the right time.
Acute coronary syndrome: What is the cost-effectiveness of prevention, point-of-care technology and telemonitoring?
September, 2012
Abstract
This study is a cost-analysis that calculates the impact of three interventions for patients identified as ‘at risk’ for Acute Coronary Syndrome – a cardio-vascular exercise programme, point-of-care digital diagnostics, and telemonitoring adherence tools. The results demonstrate that the largest impact is measured when all three interventions are utilized simultaneously producing a cumulative savings of €4424 and 0.126 QALY per patient. We also find a significant decrease in Emergency Room visits by 15% and changes in rates of utilization of Catharization (−59%), Angioplasty (−59%), Bypass (−17%), Medication (−14%) and Rehabilitation (−13%).
Unlocking the value of personalised healthcare in Europe—breast cancer stratification
June, 2012
Abstract
Through stratification, this simulation shows that there is great potential to improve the efficiency of treating breast cancer. By segmenting the female population at the age of 50 based on family history and genetic testing, our model shows a reduction in costs of breast cancer treatments by 37% with no loss of efficacy accomplished primarily through a 60% drop in incidence of metastatic stages of the disease
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EU biopharma company startups declined 50% in 2018, well before the COVID pandemic #gplhttps://t.co/issED0DVJV@amgen @abbvie @abbvieuk @IAmBiotech @DuaneSchulthess @BSBHbyVT @VitalTransform pic.twitter.com/fORbCktE8z
— VitalTransformation (@VitalTransform) April 23, 2024
New study "The EU General Pharmaceutical Legislation & Clawbacks: Calculated impacts – both designed and unintended." https://t.co/issED0DnUn@amgen @AbbVie @IAmBiotech @DuaneSchulthess @BSBHbyVT @VitalTransform @abbvieuk
— VitalTransformation (@VitalTransform) April 18, 2024
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